London, 1870

A Victorian doctor, driven by an obsessive need to find a cure for furor uterinus (more commonly known as “nymphomania”), combs the city’s asylums for sufferers. His despair grows as his bizarre experiments, searching for ways to free them from their voracious desires, only inflame their desperate maladies.

Buffalo, Present Day

A university student and his friends, cleaning up the strange house he inherited from a distant relative, discover something quite peculiar: a hidden laboratory, thick with cobwebs. Inside, they find a collection of beautifully tooled but improbable machines, Rube-Goldbergesque apparatuses wrenched from the fever dream of a mad scientist…and next to them, a faded experimental notebook detailing a series of extraordinary experiments designed to subject his female patient to extreme sexual stimulation, driving them far beyond the realms of reason.

Fuelled by curiosity, they recreate the Victorian doctor’s research, with an entirely different agenda. What they learn surprises them all.

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